Ottawa researchers aim for ‘untreatable’ strokes with new clinical trials

Ottawa stroke researchers have pushed the boundaries of patient care around the world, and they continue to do so, but it is not widely known in the city, according to an expert who wants to spread the word.

For that reason, the University of Ottawa’s annual Brain Health Awareness Week, which ended Friday, aims to showcase some of the innovative science coming out of the nation’s capital.

Dr. Dar Dowlatshahi, a stroke neurologist at Ottawa Hospital, spoke in a panel on a clinical trial he is about to begin, which will try to stop the effects of a cerebral haemorrhage, also called a cerebral haemorrhage.

“I think [it’s] the usual Ottawa phenomena where we have expertise and grandeur in our own backyard, but we always think there is something better elsewhere, “he told Alan Neal, host of CBC Radio’s Everything in one day.

Dowlatshahi says that any medium-sized or large city has researchers who are often internationally known but not locally known.

“When you go home, you go home, you do not knock on your neighbor’s door and say, ‘guess what I discovered today?’ It’s for the conferences and the meetings, “he said.

Everything in one day11:46How research in Ottawa is changing the care of stroke patients

It’s brain health awareness week at the University of Ottawa. Today, stroke researchers go on stage to talk about how the groundbreaking research they are doing in the 613s is affecting the treatment of stroke patients around the world. We talk to Dr. Dar Dowlatshahi on his work 11:46

Standard stroke treatment developed in Ottawa

A standard treatment around the world for clots was developed in Ottawa, and he hopes to be able to build on that work.

“One of the greatest landmark experiments in the world called the ESCAPE study was conceived in [ByWard] Market in Ottawa around the dinner table with about four or five of us chatting, “Dowlatshahi said.

When Dowlatshahi started in the field, very little could be done for any patient who had a stroke. Now he says that coagulation strokes could completely reverse the effects of a stroke – but there is still no method for cerebral hemorrhage.

“I look at the cerebral haemorrhage, the currently untreated stroke, as exactly where all the other strokes were. [20] years ago when I first started my medical education. ”

The clinical trial examining a treatment for cerebral haemorrhage will include 860 patients in five countries. Patients will receive an injection of placebo or a protein that occurs naturally in the body and causes the blood to clot

Responds to symptoms of stroke

Studies show that someone gets a stroke in Canada every nine minutes – which adds up to about 60,000 strokes a year. One in four of them is a cerebral hemorrhage.

The key to reversing stroke symptoms, Dowlatshahi says, is to respond quickly. Patients in the trial must have had symptoms for less than two hours to be eligible.

Fast is also a mnemonic for determining symptoms of stroke.

  • F – Facial changes suddenly, for example, get stuck.
  • A – The arm becomes weak or one side of the body stops moving.
  • S – Blurred speech or inability to speak.
  • T – Time. There is not much, call 911.

Dowlatshahi says people make two mistakes when they, or someone they are with, have a stroke. One is waiting to see if the symptoms go away on their own and the other is trying to drive himself to the hospital.

Paramedics will know where to take a patient and be able to warn stroke specialists to prepare, as there is one comprehensive stroke center in the city.

FASTEST also happens to be the name of the upcoming trial.

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